Development of Lyo Protein Products

PAT Methods for Co-Formulated mAbs

Aggregation in Frozen State Upon Dropping

HTS and HC Protein Formulations

HTS and HC Trastuzumab Formulation

Buffers and HC Lyo Formulations

Amyloid Aggregation Databases

CEX and mAb Co-Formulations

MD and Protein-Excipient Interactions

Quantitation of Surfactants using qNMR

Stabilizers for Erythopoietin (EPO)

Stabilization of Infliximab by HP-β-CD

Destabilization by Polyamines

Removal of Surfactants from mAb Solutions

2-MIDHP as a Stabilizer of mAbs

Role of Arg with Peptides and Proteins

Effect of UVC Irradiation on Lysozyme

Fe (III)/Citrate Effects on Photostability

Photodegradation of Fe(III)-Lactate

Fluorochemical Carriers for Biologics

Injectability of HC Suspensions

Hexametaphosphate as a Stabilizer

Advances in Polypeptide PEGylation

Modification Strategies for Peptides/Proteins

Effect of Cyclodextrins on ADC Stability

Sucrose vs. Trehalose as Stabilizers

Protein-Buffer Interactions by NMR

Factors Influencing Polysorbate Stability

Oleic Acid and mAb Particle Formation

Stabilization by HP-β-CD with Electrolytes

Fibrillation Inhibition by ATP

Buffer Effects on Ultrafiltration of BSA

Overview of Protein Glycation

Review of Oxidation of Food Proteins

Developability Consideration for Bispecifics

Predicting Viscosity of HC mAb Solutions

Machine Learning and LNP Development

Solid-State Behavior of Lyophilized IgG2

Impact of Sugar-to-mAb Ratio on Stability

Buffer Effects on Lyo Protonation State

Protein-Polysorbate Interactions

Insulin Aggregation

Thermal and pH Stress Effects on mAbs

Supercooling and Vaccine Stability

Condensates and Protein Aggregation

Arg Suppresses TTR Aggregation

Biologics for Pulmonary Delivery

NMR Study of Frozen Pembrolizumab

Light-Coupled NMR to Study Stability

Development of Peptide-Based Therapeutics

Analysis/Delivery of Short Peptides

Protein-Buffer Interactions by NMR

Alternative Buffer Systems for mAbs

Buffer Effects on Stability of an IgG4

Mg2+ and Heterogeneity of Trastuzumab

Crowding and Protein Aggregation

NMR Monitoring of mAb Stability

Local and Systemic Drug Delivery of mAbs

Stabilization of mAbs by Arg and Glu

Polymer-Mediated Stabilization

Guluronic Acid Disaccharide as an Additive 6 Albumin as a Surface-Active Excipient

Cryoprotectant Potential of a Zwitterion

Root Cause of Analysis of Visible Particles

Container Effects on SVP Formation

DSC to Study Peptides during Freezing

Electrochemical Biosensors for Amyloid

Microfluidic Sensor for mAb Aggregates

Biosensing Strategies for Aggregates

Summary of Aggregate Detection Methods

Initial HMW and mAb Aggregation Kinetics

Large-Volume Subcutaneous Delivery

s.c. Delivery of mAbs in Oncology

Thermal Aggregation of Proteases

Functions of Arg in Biochemistry

Reversible Complexes and s.c. Delivery

Arg Stabilization of Luciferase Enzyme

Stabilization by Lyso-Phosphatidylchloline

Stabilization by ATP at Low Temperatures

Betaine Impacts Lactoperoxidase Stability

Inhibition of Fibrillation by Sugars

Impact of Buffers in PS 80 Oxidation

Degradation of PS 20

Factors Affecting Vial Fogging

Degradation on Insulin in the Solid-State

Evaluation of Various Lyoprotectants

Transition from i.v. to s.c. Administration

Lyophilization of Parenteral Products

Deaeration/PS 80: Thin-Film Freeze-Drying

mAb Aggregation at Silicone Oil Interface

Aggregation Behavior of mAbs

Crowding and LLPS of Aβ Peptide

Tolerability of s.c. Injections

Risk Assessment for Combination Products

Predicting mAb Bioavailability

Stabilization of mAbs during Protein A

Peptide Solubilization

Aggregation of Liraglutide

Studies on Glucagon Aggregation

Protein Inclusion into Ice

Bubbles and Freeze-Induced Aggregation

Predicting Long-Term Storage Stability

Combined Shear and Interfacial Stress

Interface-Induced Protein Particle Formation

NaCl and Agitation-Induced Aggregation

Preformulation Study of a Bispecific

Effect of Sucrose and NaCl on mAb PPIs

Predicting mAb Deamidation Propensities

Freezing Drug Substance in Bottles

Directional F/T of Protein DS in Bottles

Database of Antibody Developability

Developability of Certain Small Proteins

Stability of Various Surfactants

Osmolyte-Induced Protein Stability

Stability of a Bispecific Duet Antibody

Prediction of mAb Storage Stability

Protecting Proteins during Drying Stress

Silicone Depletion in Biologics in PFS

Developability Assessment of an IgG3

Post-Manufacturing Handling of Biologics

Aggregation/Charge Heterogeneity of mAbs

Basic Variants of Trastuzumab

IEX Binding of mAb Charge Variants

CE-MS Characterization of Charge Variants

Spectroscopic Analysis of Aggregates

mAbs in Tablet Form

Interfacial and Shear Stress on mAbs

Luminescent Probe for Amyloid Formation

Charge Heterogeneity Mass Spectrometry

Stress of Transport of Immunoglobulins

Shear and Interfacial Stress of mAbs

SEC of Diverse Biopharmaceuticals

Application of QbD to SEC for mAbs

Stability of Fractionated mAb Variants

ThT as Reporter of Microviscosity

In-Use Stability of IVIG and Rituximab

Co-Solvents in Protein Formulations

Betaine Stabilization of Lactoperoxidase

Combined Effects of HP-β-CD and PS 80

Proteins in ILs and DES

Osmolyte Stabilization of RNase

Stabilization of Lysozyme in DES

Aggregation Inhibition by Arginine

Modulation of LLPS by Osmolytes

Understanding Glucagon Aggregation

Arg Inhibition of PolyQ Oligomerization

Light Effects on Low pH Unfolding of mAb

Use ArgHCl During Enzyme Spray-Drying

Effect of Co-Solutes on Barnase

Protein-Protein Cross-Interactions

Effect of Amino Acids on PPIs

Triazolium ILs and BSA Stability

Cellulases at the Air-Water Interface

Adsorption at the Water-Oil Interface

MD Simulations of Lyophilized Proteins

Review of Fluorescence-Based Methods

Fluorescence Correlation Spectroscopy

Intrinsic Fluorescence of mAbs

Stability of Protein Pharmaceuticals

Predicting Stability of Lyophilized HSA

Raman Analysis of Stressed Proteins

Manufacturing Changes for mAbs

Histidine as an Excipient for Proteins

Innovation in ADC Development

Osmolytes and PEG Effects on an Enzyme

Screening Kit for LLPS Behavior

Factors Affecting the Stability of RNA

Advances in AI for Drug Development

Effect of Aggregates on Immunogenicity

Safety of Visible Particles in Parenterals

Injectability Modeling for Prefilled Syringes

Optimizing Excipient Properties

Modeling Bi-Specifics in Aqueous Solution

Effects of mAb Charge Heterogeneity

DeepSP: Predicting mAb Stability

Fc Mutations to Reduce mAb Viscosity

Effect of PS 80 Grade on Biologics

Conversion from Vial to Injection Device

Mutations to Improve the Viscosity of mAbs

Stabilization of Lyophilized Enzymes

HES as a Cryoprotective Agent

Effect of Surfactants on mAb Analysis

Oxidation of Polysorbates

Formulation and Manufacturing of AAV

Poloxamer 188 and AAV6 Stability

Approved Oligonucleotide Products

Approved Parenteral Peptide Formulations

Phe as a Stabilizer of alpha-Amylase

Proteins in Ionic Liquids (ILs)

ILs as Drug Delivery Systems

PS 20 Degradation in Protein Formulations

Stable Peptide Nanoparticle Formulations

HC Lyophilized Protein Formulations

Effect of Stirring on Particle Formation

Protein Stability in s.c. Environment

Retinal Delivery of mAbs via Eye Drops

Polysulfobetaines as Aggregation Inhibitors

Evaluation of NTA Parameters

Products in the FDA Purple Book

Dual Function Surfactants as Excipients

Poloxamer 188 in Lyophilized Formulations

Effect of Surfactants in LDH in Solution

Particle Tracking Microrheology of mAbs

Passive Microrheology of NIST mAb

Oxidation Propensity Screening of mAbs

Adsorption of mAbs to Air-Water Interface

Ion Binding to mAbs Using MD Simulation

Stabilization of Lysozyme by Sugars

Stability of HC Spray-Dried mAbs

Mobility of Lyophilized HSA using ssNMR

Microwave Freeze Drying of IgY

Anion-Induced Aggregation of Insulin

Raman Spectroscopic Study of Insulin

Antibody Association and Cluster Formation4

Computational Methods and Aggregation

Overview of Peptide Aggregation

Anomalous Diffusion of mAbs

Machine Learning and mAb Development

Glycation of Proteins

Systemic Sublingual Delivery of Proteins

Long-Acting Antibody Drugs

Thermal Treatment of Biosimilars

mAb Aggregation at Interface under Flow

Effect of Osmolytes on Tau Aggregation

mAb Charge Variants and Aggregation

Solid-State Stability of a mAb

Reducing Reconstitution Times

Shape Effects on Viscosity of Proteins

Immunogenicity of Protein Particles

Surface Activity and Interfacial Aggregation

Cryopreservation of Mammalian Cells

Loss of CCI in a PFS at Low Temperatures

Photostability of Nivolumab

Review of Macromolecular Crowding

Effect of Sorbitol and Betaine on Lysozyme

Visible Bubbles in Lyophilized Proteins

Iron Binding and Photofragmentation

Reduction of Viscosity by Proline Analogs

Aggregation Inhibition by Arg

Effect of Tubing on PS 80 Oxidation

Glycosylation Effects on Colloidal Stability

Factors Governing Viscosity of mAbs

Safety of Subvisible Silicone Oil Droplets

Diafiltration-Induced Damage of a mAb

Agitation-Induced Aggregation of ADCs

Agitation-Induced Aggregation of Proteins

Self-Association of Fc-Fusion Proteins

Coarse-Grained Simulations of mAbs

Relaxation in Freeze-Dried Formulations

Shaking of Freeze-Dried Formulations

Ion Binding and mAb Aggregation

Poly(Glu) Derivatives as Viscosity Reducers

Osmolality of High Concentrations mAbs

Taurine as a Stabilizer of mAbs

Nano-Osmolytes as Stabilizers

Use of ILs and DES as Stabilizers

Monitoring Visible Particles in Parenterals

wNMR Characterization of HC mAbs

pH Effects on HCP Polysorbate Degradation

Heat Inactivation to Slow Polysorbate Loss

Aggregation Kinetics of PTH(1-84)

Fractionation of Protein Particulates

Potency and Stability of Charge Variants

Flow-Induced Aggregation Assay for mAbs

Salt Effects on Protein LLPS

Forced Degradation Studies: Comparability